# Introduction to Statistical Methods for Clinical Trials

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- Authors: [Thomas D. Cook](https://www.bookquiver.com/thomas-d-cook), [David DeMets](https://www.bookquiver.com/david-demets)
- Language: en_US
- Published: 2007-11-19
- Genres: Mathematics, Popular science

## Description

This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS.

## Editions

### Introduction to Statistical Methods for Clinical Trials

- Publisher: Chapman and Hall/CRC
- ISBN: 978-15-8488-027-1
- Pages: 464
- Published: 2007-11-19
- Language: en_US