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  "title": "Introduction to Statistical Methods for Clinical Trials",
  "subtitle": null,
  "url": "https://www.bookquiver.com/thomas-d-cook/introduction-to-statistical-methods-for-clinical-trials/9781584880271",
  "publisher": "Chapman and Hall/CRC",
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  "medium": "paper",
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  "isbn": "978-15-8488-027-1",
  "pages": 464,
  "published": "2007-11-19",
  "language": "en_US",
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  "binding": "Hardcover",
  "description": "This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS.",
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    "title": "Introduction to Statistical Methods for Clinical Trials",
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  "authors": [
    {
      "name": "Thomas D. Cook",
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    {
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